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Free NABP FPGEE Practice Exam with Questions & Answers

Questions 1

Which of the following is the primary site of activity for the drug Warfarin?

Options:
A.

Kidney

B.

Liver

C.

Blood

D.

Heart

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Questions 2

Given F = .24, what is the overall hepatic clearance of morphine if the above patient has portal hypertension such that their hepatic blood flow is reduced by ½? Assume the clearance value given in the previous question is entirely hepatic clearance.

Options:
A.

30 L/hr/70 Kg

B.

60 L/hr/70 Kg

C.

120 L/hr/70 Kg

D.

250 L/hr/70 Kg

Questions 3

Indication of salmeterol is:

Options:
A.

Thyrotoxicosis - preparation for surgery

B.

Chronic renal disease

C.

Scleroderma renal crisis

D.

Asthma

E.

Allergic rhinitis

Questions 4

Which of the following is not related to a drug toxicity of Prednisone?

Options:
A.

Cataracts

B.

Hypotension

C.

Psychosis

D.

Acne

Questions 5

Site of metabolism of zolpidem is:

Options:
A.

Liver

B.

None

C.

Reticuloendothelial system

D.

Leukocytes

E.

Unknown

Questions 6

Class of metformin is:

Options:
A.

Lipid lowering drugs

B.

Antimycobacterial

C.

Thyroid agents

D.

Vasodilators

E.

Oral hypoglycemics

Questions 7

Potassium sparing diuretics have the primary effect upon the _____ found in the kidney.

Options:
A.

Proximal convoluted tubule

B.

Loop of Henle

C.

Collecting duct

D.

Distal convoluted tubule

Questions 8

Mechanism of action of neomycin is:

Options:
A.

Inhibits dihydropteroate synthetase

B.

Blocks K channels

C.

Blocks Na channels

D.

Binds to 30S subunit of bacterial ribosome

E.

Inhibits mycolic acid synthesis

Questions 9

Which of the following causes the smallest change in solubility?

Options:
A.

Hydroxylation

B.

Glucuronidation

C.

Sulfation

D.

Glutathione conjugation

Questions 10

Mechanism of resistance of sufentanil is:

Options:
A.

Penicillin binding proteins (PBPs)

B.

Decreased drug uptake by bacteria

C.

Transport protein mutations

D.

Tolerance

E.

Mutation of viral DNA polymerase

Exam Code: FPGEE
Certification Provider: NABP
Exam Name: Foreign Pharmacy Graduate Equivalency Examination
Last Update: Jul 15, 2025
Questions: 426

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