Free Medical Council of Canada MCCQE Practice Exam with Questions & Answers | Set: 5

Persistent postmenopausal bleeding requires thorough evaluation. An inadequate endometrial biopsy result does not rule out pathology. Hysteroscopy allows for direct visualization and targeted biopsy and is the gold standard when biopsy is non-diagnostic.

Toronto Notes 2023 – Gynecology, “Abnormal Uterine Bleeding and Endometrial Cancer” Section:

“Persistent bleeding with insufficient biopsy requires further evaluation, preferably via hysteroscopy and directed biopsy. This is especially important in patients on HRT or with risk factors for endometrial pathology.”

MCCQE1 Objectives (Obstetrics & Gynecology > 82-9: Postmenopausal Bleeding):

“Candidates must investigate abnormal bleeding in postmenopausal women with hysteroscopy when endometrial sampling is non-diagnostic.”

Changing hormones (A), reducing progestin (E), or performing colposcopy (C) are not appropriate without confirming the cause of bleeding.

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This patient meets the definition of infertility (no conception after 12 months; here 2 years). Her day-3 FSH/LH and mid-cycle estradiol are within expected ranges, and TSH is normal, making thyroid disease unlikely. The key abnormality is elevated prolactin (40 µg/L) . MCCQE objectives emphasize identifying reversible endocrine causes of infertility: hyperprolactinemia can impair fertility by disrupting hypothalamic GnRH pulsatility and ovulatory function, and treatment improves pregnancy rates. The appropriate next management is a dopamine agonist (e.g., bromocriptine) to lower prolactin and restore normal reproductive axis function.

Pituitary MRI is generally reserved for marked or persistent elevations suggestive of prolactinoma (often much higher levels) or when there are neurologic symptoms (e.g., headaches, visual field defects). IVF is not first-line when a treatable endocrine abnormality is present. Mammography is unrelated to mild hyperprolactinemia without breast findings. Treating the elevated prolactin addresses a likely contributor before proceeding to more invasive fertility interventions.

A posterior hip dislocation is an orthopedic emergency . The classic position is a shortened limb held in flexion, adduction, and internal rotation after high-energy trauma. MCCQE objectives emphasize immediate recognition and urgent management to prevent complications, especially avascular necrosis (AVN) of the femoral head and sciatic nerve injury . The key treatment is prompt closed reduction (ideally within hours) under procedural sedation or anesthesia, after appropriate analgesia and neurovascular assessment. Post-reduction priorities include confirming concentric reduction with imaging, repeating a neurovascular exam (particularly sciatic nerve function), and evaluating for associated fractures (acetabular or femoral head/neck) that may require CT and possible operative management.

Open reduction is reserved for irreducible dislocations, incarcerated fragments, or associated fractures preventing stable closed reduction. Skeletal traction is not definitive acute management. Total hip arthroplasty is not indicated as first-line in an acute traumatic dislocation in this context. Urgent closed reduction best aligns with time-sensitive limb- and joint-preserving care.

Comprehensive and Detailed Explanation:

This patient is likely experiencing extrapyramidal symptoms (dysphagia/dystonia) due to haloperidol. Switching to an atypical antipsychotic (like quetiapine), which has a lower risk of EPS, is appropriate. Dysphagia in the context of antipsychotic use requires prompt medication review.

Toronto Notes 2023 – Psychiatry, “Antipsychotics and Extrapyramidal Effects”:

“Dysphagia can be a sign of extrapyramidal side effects. Consider switching to an atypical antipsychotic with lower EPS risk.”

MCCQE1 Objectives (Psychiatry > 71-5: Antipsychotic Adverse Effects):

“Candidates must recognize and manage EPS, including drug-induced dysphagia.”

Dantrolene (C) is for neuroleptic malignant syndrome, not isolated dysphagia. Laryngoscopy (B) may be useful later but not first-line. Reassurance (D) is unsafe. Lorazepam (E) may help in dystonia but doesn ' t address the root cause.

This presentation is most consistent with acute bronchiolitis, which classically affects infants under 2 years (peak 2–6 months) and begins with upper respiratory symptoms (coryza, cough, low-grade fever) followed by increased work of breathing, tachypnea, and wheeze. The most common causative agent is respiratory syncytial virus (RSV), making it the best answer. Parainfluenza virus is more strongly associated with croup (barking cough, inspiratory stridor, hoarseness). Chlamydia trachomatis pneumonia typically occurs in young infants with a staccato cough, afebrile course, and may be associated with conjunctivitis rather than acute wheezing after coryza. Human metapneumovirus can cause bronchiolitis-like illness but is less common than RSV. Influenza A often produces higher fever and systemic symptoms and is not the leading cause of bronchiolitis in this age group. MCCQE objectives emphasize recognizing bronchiolitis clinically and identifying RSV as the predominant pathogen in infants with this classic progression of symptoms.

Her presentation at 6 weeks after a spouse’s death is most consistent with acute/normal grief : intense sadness, crying, social withdrawal, reduced appetite, and waves of distress triggered by reminders of the deceased. MCCQE objectives stress distinguishing grief from major depressive disorder by the fluctuating nature of symptoms , grief “pangs,” and the link to thoughts of the deceased. Although she expresses wishing to “join” her husband, this can occur in normal bereavement; the key clinical duty is to assess safety (suicidal intent, plan, means, past attempts, protective factors). In the absence of imminent risk or psychosis, inpatient/day-hospital admission is not the default. “Reassurance” alone is insufficient because she is significantly impaired and needs structured support. The best next step is referral for bereavement-focused support (often via social work), which can provide grief counseling, coping strategies, mobilization of supports, and monitoring, and can facilitate escalation if complicated grief or major depression emerges. Family systems therapy may help later, but immediate practical and grief-specific support plus safety assessment is the priority.

Comprehensive and Detailed Explanation:

This patient presents with the classic triad of normal pressure hydrocephalus (NPH): gait disturbance (often wide-based and magnetic), cognitive decline, and urinary incontinence. The combination, especially with the gait being most prominent, is highly suggestive.

Toronto Notes 2023 – Geriatrics / Neurology:

“NPH presents with gait disturbance, dementia, and urinary incontinence. Gait is typically broad-based and magnetic. Imaging shows ventriculomegaly without elevated pressure.”

MCCQE1 Objectives (Geriatrics > 41-1: Cognitive Disorders):

“Candidates must identify NPH and distinguish it from other dementias based on clinical triad and gait features.”

Alzheimer’s (B) primarily presents with memory loss. Parkinson’s (A) has bradykinesia and rigidity. Lewy body dementia (C) includes visual hallucinations and fluctuating cognition. FTD (E) has personality and behavioral changes.

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A confounder is a variable associated with both the exposure and the outcome but not in the causal pathway. In this study, coffee drinking is associated with smoking (the actual risk factor for lung cancer), but not independently associated with lung cancer.

Toronto Notes 2023 – Epidemiology Chapter:

“A confounder is a third variable that distorts the observed association between an exposure and an outcome. It must be associated with both the exposure and the outcome, but not a result of the exposure.”

MCCQE1 Objectives (Population Health > 97-3: Study Design and Bias):

“Recognize and control for confounding in the interpretation of observational study data.”

Coffee is not a risk factor (B) since it’s not independently associated with lung cancer, and it ' s not selection bias (C), which involves how participants are enrolled in a study.

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This is a classic presentation of diabetic peripheral neuropathy: bilateral distal sensory symptoms with preserved motor function and no other systemic findings. The most useful test to confirm this in a previously undiagnosed patient is HbA1c.

Toronto Notes 2023 – Endocrinology, Diabetes Complications:

“Peripheral neuropathy is a common complication of undiagnosed or poorly controlled diabetes. Confirm with HbA1c if diagnosis is not yet established.”

MCCQE1 Objectives – Internal Medicine > Endocrinology:

“Candidates should evaluate for diabetes in patients with peripheral neuropathy and screen appropriately with HbA1c.”

Folate (B) and B12 deficiency may also cause neuropathy but are less likely in the absence of nutritional risk factors. Other choices (A, D, E) are unrelated to this pattern.

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This ABG reveals primary respiratory acidosis (↓pH, ↑PaCO₂, normal HCO₃), likely from hypoventilation due to postoperative pain, sedation, or narcotics. PaO₂ is also low, suggesting inadequate oxygenation.

Toronto Notes 2023 – Respiratory, “Postoperative Respiratory Complications”:

“Postoperative respiratory acidosis results from hypoventilation, often due to pain, sedatives, or poor respiratory effort. Assess airway, breathing, and support oxygenation.”

MCCQE1 Objectives (Internal Medicine > 44-3: Acid-Base Disturbances):

“Candidates must recognize respiratory acidosis on ABG and relate findings to common postoperative complications.”

Metabolic acidosis (C) would show ↓HCO₃. Compensated alkalosis (D) would show opposite ABG changes. Hypermetabolic states increase respiratory drive, not decrease it.